Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.

Powell, Jason A

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. [electronic resource] - Blood Nov 2009 - 4859-70 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2009-02-204818 doi


Adult
Aged
Cell Survival
Cytokine Receptor Common beta Subunit--metabolism
Female
Gene Expression Profiling
Gene Expression Regulation, Leukemic
Gene Knockdown Techniques
Gene Regulatory Networks
Hematopoietic Stem Cells--drug effects
Humans
Leukemia, Myeloid--genetics
Male
Middle Aged
Neoplasm Proteins--genetics
Neoplastic Stem Cells--drug effects
Osteopontin--biosynthesis
Phosphatidylinositol 3-Kinases--physiology
Phosphoinositide-3 Kinase Inhibitors
Phosphoserine--metabolism
Prognosis
RNA, Messenger--biosynthesis
RNA, Neoplasm--biosynthesis
RNA, Small Interfering--pharmacology
Signal Transduction--genetics
Tumor Cells, Cultured--drug effects