Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo.

Perez, Michel

Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo. [electronic resource] - Journal of medicinal chemistry Oct 2009 - 5826-36 p. digital

Publication Type: Journal Article

1520-4804

10.1021/jm900553j doi


Animals
Drug Discovery
Drug-Related Side Effects and Adverse Reactions
Fibrinolytic Agents--administration & dosage
Humans
Piperazines--pharmacology
Platelet Aggregation Inhibitors--administration & dosage
Pyridines--pharmacology
Rats
Structure-Activity Relationship