Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats.

Scholz, M

Pharmacokinetic and pharmacodynamic modelling of the novel human granulocyte colony-stimulating factor derivative Maxy-G34 and pegfilgrastim in rats. [electronic resource] - Cell proliferation Dec 2009 - 823-37 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1365-2184

10.1111/j.1365-2184.2009.00641.x doi


Animals
Antineoplastic Agents--adverse effects
Cyclophosphamide--adverse effects
Filgrastim
Granulocyte Colony-Stimulating Factor--pharmacokinetics
Humans
Male
Models, Biological
Neutropenia--chemically induced
Polyethylene Glycols--pharmacokinetics
Rats
Rats, Sprague-Dawley
Recombinant Proteins