Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.

Chen, Ku-Chung

Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells. [electronic resource] - Journal of cellular physiology Jan 2010 - 177-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1097-4652

10.1002/jcp.21934 doi


Activating Transcription Factor 2--metabolism
Anthracenes--pharmacology
Apoptosis--drug effects
Calcium--pharmacology
Caspase 9--metabolism
Cell Line, Tumor
Down-Regulation--drug effects
Egtazic Acid--analogs & derivatives
Elapid Venoms--pharmacology
Enzyme Activation--drug effects
Humans
Imidazoles--pharmacology
JNK Mitogen-Activated Protein Kinases--metabolism
Membrane Potential, Mitochondrial--drug effects
Mitogen-Activated Protein Kinases--metabolism
Neuroblastoma--enzymology
Proto-Oncogene Proteins c-fos--metabolism
Proto-Oncogene Proteins c-jun--metabolism
Pyridines--pharmacology
Reactive Oxygen Species--metabolism
Signal Transduction--drug effects
Up-Regulation--drug effects
bcl-2 Homologous Antagonist-Killer Protein--metabolism
bcl-X Protein--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism