Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility.

Cygalova, Lenka Hahnova

Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: effect of drug efflux transporters and lipid solubility. [electronic resource] - The Journal of pharmacology and experimental therapeutics Dec 2009 - 1118-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.109.160564 doi


ATP Binding Cassette Transporter, Subfamily B, Member 1--metabolism
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--metabolism
Animals
Biological Transport
Boron Compounds--chemistry
Dose-Response Relationship, Drug
Female
Glyburide--chemistry
In Vitro Techniques
Lipids--chemistry
Maternal-Fetal Exchange
Perfusion
Placenta--metabolism
Prazosin--analogs & derivatives
Pregnancy
Rats
Rhodamine 123--chemistry
Solubility
Substrate Specificity