Incomplete formation of intramolecular disulfide bond triggers degradation and aggregation of human consensus interferon-alpha mutant by Pichia pastoris.
Wu, Dan
Incomplete formation of intramolecular disulfide bond triggers degradation and aggregation of human consensus interferon-alpha mutant by Pichia pastoris. [electronic resource] - Applied microbiology and biotechnology Feb 2010 - 1759-67 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1432-0614
10.1007/s00253-009-2232-0 doi
Bioreactors
Disulfides--metabolism
Electrophoresis, Gel, Two-Dimensional
Fermentation
Humans
Interferon-alpha--biosynthesis
Mutation
Pichia--genetics
Protein Stability
Recombinant Proteins--biosynthesis
Incomplete formation of intramolecular disulfide bond triggers degradation and aggregation of human consensus interferon-alpha mutant by Pichia pastoris. [electronic resource] - Applied microbiology and biotechnology Feb 2010 - 1759-67 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1432-0614
10.1007/s00253-009-2232-0 doi
Bioreactors
Disulfides--metabolism
Electrophoresis, Gel, Two-Dimensional
Fermentation
Humans
Interferon-alpha--biosynthesis
Mutation
Pichia--genetics
Protein Stability
Recombinant Proteins--biosynthesis