The dexamethasone-induced inhibition of proliferation, migration, and invasion in glioma cell lines is antagonized by macrophage migration inhibitory factor (MIF) and can be enhanced by specific MIF inhibitors.

Piette, Caroline

The dexamethasone-induced inhibition of proliferation, migration, and invasion in glioma cell lines is antagonized by macrophage migration inhibitory factor (MIF) and can be enhanced by specific MIF inhibitors. [electronic resource] - The Journal of biological chemistry Nov 2009 - 32483-92 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1083-351X

10.1074/jbc.M109.014589 doi


Antineoplastic Agents, Hormonal--pharmacology
Brain Neoplasms--metabolism
Cell Line, Tumor
Cell Movement
Cell Proliferation
Dexamethasone--pharmacology
Dose-Response Relationship, Drug
Gene Expression Regulation
Glioma--metabolism
Humans
Macrophage Migration-Inhibitory Factors--antagonists & inhibitors
Mitogen-Activated Protein Kinase 3--metabolism
Models, Biological
Neoplasm Invasiveness
Time Factors