A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry.

Baleux, Françoise

A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry. [electronic resource] - Nature chemical biology Oct 2009 - 743-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1552-4469

10.1038/nchembio.207 doi


Anti-HIV Agents--chemistry
Binding Sites
CD4 Antigens--chemistry
Glycoconjugates--chemistry
HIV Envelope Protein gp120--metabolism
HIV-1--drug effects
Heparitin Sulfate--chemistry
Humans
Leukocytes, Mononuclear--drug effects
Models, Molecular
Receptors, CCR5--metabolism
Receptors, CXCR4--metabolism
Virus Attachment--drug effects
Virus Internalization--drug effects