Cytokine interactions in experimental cutaneous leishmaniasis. II. Endogenous tumor necrosis factor-alpha production by macrophages is induced by the synergistic action of interferon (IFN)-gamma and interleukin (IL) 4 and accounts for the antiparasitic effect mediated by IFN-gamma and IL 4.

Stenger, S

Cytokine interactions in experimental cutaneous leishmaniasis. II. Endogenous tumor necrosis factor-alpha production by macrophages is induced by the synergistic action of interferon (IFN)-gamma and interleukin (IL) 4 and accounts for the antiparasitic effect mediated by IFN-gamma and IL 4. [electronic resource] - European journal of immunology Jul 1991 - 1669-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0014-2980

10.1002/eji.1830210713 doi


Animals
Drug Synergism
Female
Interferon-gamma--pharmacology
Interleukin-4--pharmacology
Leishmania tropica--drug effects
Leishmaniasis--metabolism
Lipopolysaccharides--pharmacology
Macrophages--metabolism
Mice
Mice, Inbred BALB C
Tumor Necrosis Factor-alpha--biosynthesis