The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors.
Holmes, Ian P
The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Oct 2009 - 5760-3 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2009.07.155 doi
Animals
Binding Sites
Carboxylic Acids--chemical synthesis
Crystallography, X-Ray
Drug Design
Guinea Pigs
Humans
Matrix Metalloproteinase 12--metabolism
Matrix Metalloproteinase Inhibitors
Protease Inhibitors--chemical synthesis
Structure-Activity Relationship
The identification of beta-hydroxy carboxylic acids as selective MMP-12 inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters Oct 2009 - 5760-3 p. digital
Publication Type: Journal Article
1464-3405
10.1016/j.bmcl.2009.07.155 doi
Animals
Binding Sites
Carboxylic Acids--chemical synthesis
Crystallography, X-Ray
Drug Design
Guinea Pigs
Humans
Matrix Metalloproteinase 12--metabolism
Matrix Metalloproteinase Inhibitors
Protease Inhibitors--chemical synthesis
Structure-Activity Relationship