Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.

Calvo, Fernando

Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors. [electronic resource] - Molecular biology of the cell Oct 2009 - 4289-302 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1939-4586

10.1091/mbc.e09-03-0212 doi


Animals
COS Cells--metabolism
Chlorocebus aethiops
Enzyme Activation--drug effects
Guanosine Diphosphate--metabolism
HeLa Cells--metabolism
Humans
Ionomycin--pharmacology
Lysophospholipids--pharmacology
Membrane Proteins--chemistry
Monomeric GTP-Binding Proteins--chemistry
Organelles--metabolism
Prenylation
Protein Interaction Mapping
Protein Processing, Post-Translational
Protein Structure, Tertiary
RNA, Small Interfering--pharmacology
Recombinant Fusion Proteins--physiology
Structure-Activity Relationship
Subcellular Fractions--metabolism
Substrate Specificity
cdc42 GTP-Binding Protein--physiology
ras Guanine Nucleotide Exchange Factors--antagonists & inhibitors
ras-GRF1--genetics