RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway.

Keuling, Angela M

RNA silencing of Mcl-1 enhances ABT-737-mediated apoptosis in melanoma: role for a caspase-8-dependent pathway. [electronic resource] - PloS one Aug 2009 - e6651 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0006651 doi


Apoptosis--drug effects
Biphenyl Compounds--pharmacology
Caspase 8--genetics
Cell Line, Tumor
Gene Knockdown Techniques
Humans
Melanoma--enzymology
Myeloid Cell Leukemia Sequence 1 Protein
Nitrophenols--pharmacology
Piperazines--pharmacology
Polymorphism, Genetic
Proto-Oncogene Proteins c-bcl-2--genetics
RNA Interference
Sulfonamides--pharmacology