Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling.

Masood, Anbrin

Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. [electronic resource] - The Journal of pharmacology and experimental therapeutics Nov 2009 - 690-9 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-0103

10.1124/jpet.109.156729 doi


Animals
Anti-Anxiety Agents
Behavior, Animal--drug effects
Cells, Cultured
Cyclic AMP--metabolism
Cyclic GMP--physiology
Enzyme Inhibitors--pharmacology
Exonucleases--antagonists & inhibitors
Guanylate Cyclase--antagonists & inhibitors
Imidazoles--pharmacology
Male
Mice
Mice, Inbred ICR
NG-Nitroarginine Methyl Ester--pharmacology
Neurons--drug effects
Nitric Oxide Donors--pharmacology
Oxadiazoles--pharmacology
Phosphodiesterase Inhibitors--pharmacology
Quinoxalines--pharmacology
Rats
Recombinant Proteins--chemistry
Signal Transduction--drug effects
Triazines--pharmacology