TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells.

Kaiser, Frank

TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. [electronic resource] - The Journal of experimental medicine Aug 2009 - 1863-71 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20091059 doi


Animals
Cytokines--metabolism
DNA Primers--genetics
DNA, Complementary--genetics
Dendritic Cells--metabolism
Enzyme-Linked Immunosorbent Assay
Gene Expression Regulation--immunology
Immunoblotting
Interferon-beta--biosynthesis
Interleukin-10--biosynthesis
MAP Kinase Kinase Kinases--genetics
Macrophages--metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Proto-Oncogene Proteins--genetics
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction--genetics