Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade.

Tang, Xue-Lian

Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade. [electronic resource] - Biological & pharmaceutical bulletin Aug 2009 - 1399-405 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1347-5215

10.1248/bpb.32.1399 doi


Animals
Antineoplastic Agents, Phytogenic--chemistry
Apoptosis--drug effects
Blotting, Western
Caspase 3--metabolism
Caspase 9--metabolism
Cell Cycle--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Centella--chemistry
Chromatin--metabolism
Colonic Neoplasms--pathology
Colorectal Neoplasms--pathology
Cytochromes c--metabolism
DNA Fragmentation--drug effects
Flow Cytometry
Humans
Membrane Potential, Mitochondrial--drug effects
Mice
Mice, Inbred BALB C
Microscopy, Confocal
Microscopy, Fluorescence
Mitochondria--drug effects
Molecular Structure
Pentacyclic Triterpenes
Poly Adenosine Diphosphate Ribose--metabolism
Stomach Neoplasms--pathology
Triterpenes--chemistry