Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.

Trageser, Daniel

Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function. [electronic resource] - The Journal of experimental medicine Aug 2009 - 1739-53 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20090004 doi


Adaptor Proteins, Signal Transducing--physiology
Adult
Animals
Cell Cycle
Cell Transformation, Neoplastic--genetics
Down-Regulation
Gene Deletion
Genes, abl
Humans
Ikaros Transcription Factor--deficiency
Leukemia, Prolymphocytic, B-Cell--genetics
Mice
Mice, Knockout
Mice, Transgenic
Philadelphia Chromosome
Pre-B Cell Receptors--deficiency
Signal Transduction