Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.

Whaley-Connell, Adam

Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat. [electronic resource] - American journal of nephrology 2009 - 354-60 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1421-9670

10.1159/000229305 doi


Animals
Antihypertensive Agents--pharmacology
Benzopyrans--pharmacology
Blood Pressure--drug effects
Disease Models, Animal
Ethanolamines--pharmacology
Hypertension, Renal--drug therapy
NADPH Oxidases--metabolism
Nebivolol
Nitric Oxide--metabolism
Nitric Oxide Synthase Type III--metabolism
Oxidative Stress--physiology
Podocytes--drug effects
Proteinuria--drug therapy
Rats
Rats, Sprague-Dawley
Rats, Transgenic
Reactive Oxygen Species--metabolism
Renin--genetics
Renin-Angiotensin System--drug effects
Tyrosine--analogs & derivatives