Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds.

MacLeod, A Kenneth

Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds. [electronic resource] - Carcinogenesis Sep 2009 - 1571-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2180

10.1093/carcin/bgp176 doi


20-Hydroxysteroid Dehydrogenases--genetics
Basic-Leucine Zipper Transcription Factors--physiology
Cells, Cultured
Cytoprotection
Fanconi Anemia Complementation Group Proteins--physiology
Gene Expression Profiling
Glutathione--metabolism
Heme Oxygenase-1--genetics
Humans
Hydroxysteroid Dehydrogenases--genetics
Intracellular Signaling Peptides and Proteins--genetics
Kelch-Like ECH-Associated Protein 1
Keratinocytes--metabolism
Keratins--genetics
NF-E2-Related Factor 2--physiology
Neoplasms--prevention & control
Response Elements
Signal Transduction