Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism.

Fujita, S

Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism. [electronic resource] - Diabetologia Sep 2009 - 1889-98 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1432-0428

10.1007/s00125-009-1430-8 doi


Animals
Biopsy
Blood Glucose--metabolism
Body Mass Index
Female
Femoral Artery--drug effects
Humans
Hyperinsulinism--pathology
Insulin--administration & dosage
Insulin Resistance--physiology
Leg--blood supply
Male
Metabolism
Muscle Proteins--biosynthesis
Muscle, Skeletal--pathology
Reference Values
Regional Blood Flow--drug effects