Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome.

Roumenina, Lubka T

Hyperfunctional C3 convertase leads to complement deposition on endothelial cells and contributes to atypical hemolytic uremic syndrome. [electronic resource] - Blood Sep 2009 - 2837-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1528-0020

10.1182/blood-2009-01-197640 doi


Adolescent
Adult
Aged
Aged, 80 and over
Cells, Cultured
Child
Child, Preschool
Cohort Studies
Complement Activation--genetics
Complement C3-C5 Convertases--genetics
Complement System Proteins--genetics
Endothelial Cells--metabolism
Family
Female
Hemolytic-Uremic Syndrome--genetics
Humans
Infant
Infant, Newborn
Male
Middle Aged
Models, Molecular
Mutant Proteins--physiology
Pedigree
Young Adult