Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease.

Midwood, Kim

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease. [electronic resource] - Nature medicine Jul 2009 - 774-80 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1546-170X

10.1038/nm.1987 doi


Animals
Arthritis--etiology
Cells, Cultured
Cytokines--biosynthesis
Humans
Lipopolysaccharides--toxicity
Mice
Myeloid Differentiation Factor 88--physiology
Protein Structure, Tertiary
Tenascin--chemistry
Toll-Like Receptor 4--physiology