Assessment of genomic instability in normal and diabetic rats treated with metformin.

Attia, S M

Assessment of genomic instability in normal and diabetic rats treated with metformin. [electronic resource] - Chemico-biological interactions Jul 2009 - 296-304 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7786

10.1016/j.cbi.2009.03.001 doi


Animals
Chromosome Aberrations--chemically induced
Diabetes Mellitus, Experimental--genetics
Drug Administration Schedule
Genomic Instability--drug effects
Glutathione--metabolism
Hypoglycemic Agents--administration & dosage
Lipid Peroxidation--drug effects
Male
Malondialdehyde--metabolism
Metformin--administration & dosage
Micronuclei, Chromosome-Defective--chemically induced
Mitosis--drug effects
Oxidative Stress--drug effects
Rats
Rats, Wistar
Reactive Oxygen Species--metabolism
Sperm Motility--drug effects
Spermatozoa--drug effects