PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma.

Petrella, Brenda L

PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma. [electronic resource] - Cancer biology & therapy Jul 2009 - 1389-401 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1555-8576

10.4161/cbt.8.14.8880 doi


Basic Helix-Loop-Helix Transcription Factors--biosynthesis
Carcinoma, Renal Cell--genetics
Cell Line, Tumor--metabolism
Cell Transformation, Neoplastic--genetics
Gene Expression Regulation, Neoplastic
Humans
Intracellular Signaling Peptides and Proteins--physiology
Kidney Neoplasms--genetics
Matrix Metalloproteinase 14--biosynthesis
Neoplasm Proteins--biosynthesis
PTEN Phosphohydrolase--physiology
Phosphatidylinositol 3-Kinases--physiology
Protein Serine-Threonine Kinases--physiology
Proto-Oncogene Proteins c-akt--physiology
Signal Transduction--genetics
TOR Serine-Threonine Kinases
Von Hippel-Lindau Tumor Suppressor Protein--genetics
YY1 Transcription Factor--antagonists & inhibitors