Chitosan-hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma.

Oyarzun-Ampuero, F A

Chitosan-hyaluronic acid nanoparticles loaded with heparin for the treatment of asthma. [electronic resource] - International journal of pharmaceutics Nov 2009 - 122-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-3476

10.1016/j.ijpharm.2009.04.009 doi


Algorithms
Animals
Anti-Asthmatic Agents--administration & dosage
Asthma--drug therapy
Cell Degranulation--drug effects
Cell Survival--drug effects
Chitosan--chemistry
Dose-Response Relationship, Drug
Drug Carriers--administration & dosage
Drug Delivery Systems--methods
Drug Stability
Endocytosis--physiology
Female
Heparin--administration & dosage
Heparin, Low-Molecular-Weight--chemistry
Histamine Release--drug effects
Hyaluronic Acid--chemistry
Inhibitory Concentration 50
Mast Cells--pathology
Nanoparticles--chemistry
Particle Size
Rats
Rats, Sprague-Dawley
p-Methoxy-N-methylphenethylamine--metabolism