1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients.

Masoumi, Ava

1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. [electronic resource] - Journal of Alzheimer's disease : JAD 2009 - 703-17 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1875-8908

10.3233/JAD-2009-1080 doi


Aged
Aged, 80 and over
Alzheimer Disease--metabolism
Amyloid beta-Peptides--metabolism
Cells, Cultured
Cholecalciferol--analogs & derivatives
Cognition Disorders--metabolism
Curcumin--analogs & derivatives
Diarylheptanoids
Dose-Response Relationship, Drug
Drug Interactions
Female
Gene Expression Regulation--drug effects
Humans
Liver--drug effects
Macrophages--classification
Male
Middle Aged
N-Acetylglucosaminyltransferases--genetics
Peptide Fragments--metabolism
Phagocytosis--drug effects
Protein Structure, Tertiary--genetics
Receptors, Calcitriol--genetics
Time Factors
Toll-Like Receptor 1--genetics
Transfection--methods