PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles.

Reddy, Pradeep

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles. [electronic resource] - Human molecular genetics Aug 2009 - 2813-24 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1460-2083

10.1093/hmg/ddp217 doi


3-Phosphoinositide-Dependent Protein Kinases
Aging--metabolism
Animals
Female
Humans
Life Expectancy
Male
Mice
Mice, Inbred C57BL
Mice, Knockout
Oocytes--cytology
Ovarian Follicle--cytology
Protein Serine-Threonine Kinases--genetics
Ribosomal Protein S6--genetics
Ribosomal Protein S6 Kinases--genetics
Signal Transduction