Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients.

Bonehill, Aude

Single-step antigen loading and activation of dendritic cells by mRNA electroporation for the purpose of therapeutic vaccination in melanoma patients. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research May 2009 - 3366-75 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1078-0432

10.1158/1078-0432.CCR-08-2982 doi


Antigens, Neoplasm--genetics
CD27 Ligand--genetics
Cancer Vaccines--genetics
Cytokines--metabolism
Dendritic Cells--cytology
Electroporation--methods
Female
Flow Cytometry
Humans
Lysosomal-Associated Membrane Protein 1--metabolism
MART-1 Antigen
Male
Melanoma--immunology
Membrane Glycoproteins--genetics
Monophenol Monooxygenase--genetics
Neoplasm Proteins--genetics
Neoplasm Staging
RNA, Messenger--genetics
Toll-Like Receptor 4--genetics
Tumor Necrosis Factor Receptor Superfamily, Member 9--metabolism
Vaccination--methods
gp100 Melanoma Antigen