A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta.

Faili, Ahmad

A backup role of DNA polymerase kappa in Ig gene hypermutation only takes place in the complete absence of DNA polymerase eta. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) May 2009 - 6353-9 p. digital

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

1550-6606

10.4049/jimmunol.0900177 doi


Adult
Animals
B-Lymphocytes--enzymology
DNA Mutational Analysis
DNA-Directed DNA Polymerase--genetics
Female
Humans
Mice
Mice, Knockout
Mutation
RNA, Messenger--analysis
Reverse Transcriptase Polymerase Chain Reaction
Somatic Hypermutation, Immunoglobulin--genetics
Xeroderma Pigmentosum--enzymology