Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival.

Wagner, Jill M

Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival. [electronic resource] - Molecular pharmacology Jul 2009 - 208-14 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.109.055178 doi


Antineoplastic Agents--pharmacology
Ataxia Telangiectasia Mutated Proteins
Cell Cycle Proteins--physiology
Cell Line, Tumor
Cell Survival--drug effects
Checkpoint Kinase 1
Cisplatin--pharmacology
DNA Damage
DNA Repair--drug effects
Humans
Protein Kinases--physiology
Protein Serine-Threonine Kinases--physiology
S Phase--drug effects