Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.

Kalayarasan, Srinivasan

Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats. [electronic resource] - European journal of pharmacology Mar 2009 - 162-71 p. digital

Publication Type: Journal Article

1879-0712

10.1016/j.ejphar.2008.12.055 doi


Allyl Compounds--pharmacology
Animals
Anti-Inflammatory Agents--pharmacology
Antioxidants--pharmacology
Ascorbic Acid--metabolism
Biomarkers--metabolism
Enzyme Induction--drug effects
Gentamicins--toxicity
Glutathione--metabolism
Inflammation--drug therapy
Kidney--drug effects
Kidney Glomerulus--drug effects
Kidney Tubules--drug effects
Lipid Peroxidation--drug effects
Male
NF-E2-Related Factor 2--metabolism
NF-kappa B--metabolism
Nitric Oxide Synthase Type II--metabolism
Oxidative Stress--drug effects
Peroxidase--metabolism
Rats
Rats, Wistar
Sulfides--pharmacology
Tumor Necrosis Factor-alpha--metabolism
Vitamin E--metabolism