Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.
Cosgrove, Benjamin D
Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. [electronic resource] - Toxicology and applied pharmacology Jun 2009 - 317-30 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2009.04.002 doi
Animals
Apoptosis--drug effects
Cell Line, Tumor
Cells, Cultured
Chemical and Drug Induced Liver Injury--metabolism
Cytokines--classification
Drug Delivery Systems--methods
Drug Evaluation, Preclinical--methods
Drug Synergism
Drug-Related Side Effects and Adverse Reactions
Hepatocytes--drug effects
Humans
Inflammation Mediators--classification
Male
Pharmaceutical Preparations--classification
Rats
Rats, Inbred F344
Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity. [electronic resource] - Toxicology and applied pharmacology Jun 2009 - 317-30 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1096-0333
10.1016/j.taap.2009.04.002 doi
Animals
Apoptosis--drug effects
Cell Line, Tumor
Cells, Cultured
Chemical and Drug Induced Liver Injury--metabolism
Cytokines--classification
Drug Delivery Systems--methods
Drug Evaluation, Preclinical--methods
Drug Synergism
Drug-Related Side Effects and Adverse Reactions
Hepatocytes--drug effects
Humans
Inflammation Mediators--classification
Male
Pharmaceutical Preparations--classification
Rats
Rats, Inbred F344