Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains.

Williams, Neal K

Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. [electronic resource] - Journal of molecular biology Mar 2009 - 219-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1089-8638

10.1016/j.jmb.2009.01.041 doi


Crystallography, X-Ray
Humans
Janus Kinases--antagonists & inhibitors
Models, Molecular
Protein Conformation
Protein Kinase Inhibitors--chemistry
Substrate Specificity