Vascular endothelial cells and smooth muscle cells mediate carbachol-induced hepatocyte proliferation via muscarinic receptors and IP3/PKC signaling cascades.

Yoshimura, Ryoichi

Vascular endothelial cells and smooth muscle cells mediate carbachol-induced hepatocyte proliferation via muscarinic receptors and IP3/PKC signaling cascades. [electronic resource] - Cell biology international Apr 2009 - 516-23 p. digital

Publication Type: Journal Article

1095-8355

10.1016/j.cellbi.2009.01.018 doi


Acetylcholine--agonists
Animals
Carbachol--pharmacology
Cattle
Cell Line
Cell Proliferation
Cholinergic Agonists--pharmacology
Coculture Techniques
Endothelium, Vascular--cytology
Enzyme Inhibitors--pharmacology
Hepatocytes--cytology
Indoles--pharmacology
Inositol 1,4,5-Trisphosphate Receptors--antagonists & inhibitors
Macrocyclic Compounds--pharmacology
Maleimides--pharmacology
Muscarinic Antagonists--pharmacology
Muscle, Smooth, Vascular--cytology
Oxazoles--pharmacology
Proliferating Cell Nuclear Antigen--metabolism
Protein Kinase C--antagonists & inhibitors
Rabbits
Rats
Receptors, Muscarinic--drug effects
Signal Transduction--drug effects