Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of merlin.

Okada, Masashi

Akt phosphorylation of merlin enhances its binding to phosphatidylinositols and inhibits the tumor-suppressive activities of merlin. [electronic resource] - Cancer research May 2009 - 4043-51 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

1538-7445

10.1158/0008-5472.CAN-08-3931 doi


Apoptosis--physiology
Cell Movement--physiology
HCT116 Cells
Humans
Hyaluronan Receptors--metabolism
Liposomes--chemistry
Molecular Conformation
Neurilemmoma--metabolism
Neurofibromin 2--antagonists & inhibitors
Phosphatidylinositols--chemistry
Phosphorylation
Protein Binding
Proto-Oncogene Proteins c-akt--metabolism