Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation.

Debenham, John S

Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation. [electronic resource] - Bioorganic & medicinal chemistry letters May 2009 - 2591-4 p. digital

Publication Type: Journal Article

1464-3405

10.1016/j.bmcl.2009.03.005 doi


Administration, Oral
Animals
Cannabinoid Receptor Agonists
Cannabinoids--chemistry
Chemistry, Pharmaceutical--methods
Drug Design
Humans
Inhibitory Concentration 50
Obesity--drug therapy
Protein Structure, Tertiary
Pyrimidines--chemistry
Rats
Receptor, Cannabinoid, CB1--agonists
Receptor, Cannabinoid, CB2--agonists
Structure-Activity Relationship