Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.

Entrena, José M

Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. [electronic resource] - Psychopharmacology Jul 2009 - 21-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-2072

10.1007/s00213-009-1513-8 doi


Analysis of Variance
Animals
Brain--cytology
Capsaicin--pharmacology
Disease Models, Animal
Dopamine Antagonists--pharmacology
Dose-Response Relationship, Drug
Female
Haloperidol--analogs & derivatives
Hyperalgesia--chemically induced
Mice
Morpholines--pharmacology
Motor Activity--drug effects
Naloxone--pharmacology
Narcotic Antagonists--pharmacology
Pain--drug therapy
Pain Measurement
Pain Threshold--drug effects
Pentazocine--metabolism
Physical Stimulation--adverse effects
Protein Binding--drug effects
Radioligand Assay--methods
Reaction Time--drug effects
Receptors, sigma--agonists
Rotarod Performance Test
Tritium--metabolism
Sigma-1 Receptor