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Chew, Phyllis

Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse. [electronic resource] - Arteriosclerosis, thrombosis, and vascular biology Jun 2009 - 823-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

ISSN: 1524-4636

Standard No.: 10.1161/ATVBAHA.109.186619 doi

Subjects--Topical Terms:
Administration, Oral
Animals
Antioxidants--administration & dosage
Aorta, Abdominal--drug effects
Aorta, Thoracic--drug effects
Aortic Diseases--etiology
Apolipoproteins E--deficiency
Atherosclerosis--etiology
Azoles--administration & dosage
Cells, Cultured
Diabetes Mellitus, Experimental--complications
Diabetic Angiopathies--etiology
Endothelial Cells--drug effects
Glutathione Peroxidase--deficiency
Humans
I-kappa B Kinase--metabolism
Isoindoles
JNK Mitogen-Activated Protein Kinases--metabolism
Macrophages--drug effects
Male
Membrane Glycoproteins--metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Muscle, Smooth, Vascular--drug effects
NADPH Oxidase 2
NADPH Oxidases--metabolism
Organoselenium Compounds--administration & dosage
Phenotype
Phosphorylation
Receptor for Advanced Glycation End Products
Receptors, Immunologic--metabolism
Time Factors
Tumor Necrosis Factor-alpha--metabolism
Tyrosine--analogs & derivatives
Vascular Endothelial Growth Factor A--metabolism
Glutathione Peroxidase GPX1