Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns.

Lao, Victoria Valinluck

Incorporation of 5-chlorocytosine into mammalian DNA results in heritable gene silencing and altered cytosine methylation patterns. [electronic resource] - Carcinogenesis May 2009 - 886-93 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1460-2180

10.1093/carcin/bgp060 doi


Animals
CHO Cells
Cricetinae
Cricetulus
Cytosine--analogs & derivatives
DNA--biosynthesis
DNA Damage
DNA Replication
Gene Silencing
Glycine--analogs & derivatives
Humans
Inflammation--genetics
Mammals
Methylation
Neoplasms--genetics
Oligonucleotides--biosynthesis