Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.

Ingold, Barbara

Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors. [electronic resource] - PloS one 2009 - e4775 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0004775 doi


Alkylating Agents--therapeutic use
Brain Neoplasms--diagnosis
Breast Neoplasms--pathology
DNA Methylation
DNA Modification Methylases--analysis
DNA Repair Enzymes--analysis
Dacarbazine--analogs & derivatives
Immunohistochemistry
Kidney Neoplasms--pathology
Lung Neoplasms--pathology
Melanoma--pathology
Polymerase Chain Reaction
Promoter Regions, Genetic
Temozolomide
Tumor Suppressor Proteins--analysis