Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.

Amiable, Nathalie

Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. [electronic resource] - Bone Jun 2009 - 1143-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2763

10.1016/j.bone.2009.02.015 doi


Aged
Aged, 80 and over
Bone Resorption--metabolism
Cells, Cultured
Dinoprostone--pharmacology
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Humans
Interleukin-17--pharmacology
Interleukin-1beta--pharmacology
Interleukin-6--pharmacology
Matrix Metalloproteinase 1--metabolism
Matrix Metalloproteinase 13--metabolism
Matrix Metalloproteinase 9--metabolism
Middle Aged
Osteoarthritis--metabolism
Osteoblasts--drug effects
RANK Ligand--genetics
Receptor, PAR-2--genetics
Reverse Transcriptase Polymerase Chain Reaction
Transforming Growth Factor beta1--pharmacology
Tumor Necrosis Factor-alpha--pharmacology