Identifying the proteins to which small-molecule probes and drugs bind in cells.

Ong, Shao-En

Identifying the proteins to which small-molecule probes and drugs bind in cells. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Mar 2009 - 4617-22 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1091-6490

10.1073/pnas.0900191106 doi


Carbazoles--metabolism
HeLa Cells
Humans
Immunophilins--chemistry
Indole Alkaloids--metabolism
Isotope Labeling
Ligands
Microspheres
Microtubule-Associated Proteins--metabolism
Molecular Probes--metabolism
Pharmaceutical Preparations--metabolism
Protein Kinase Inhibitors--metabolism
Protein Kinases--metabolism
Proteins--metabolism
Proteomics
Solubility