Integrity of H1 helix in prion protein revealed by molecular dynamic simulations to be especially vulnerable to changes in the relative orientation of H1 and its S1 flank.

Tseng, Chih-Yuan

Integrity of H1 helix in prion protein revealed by molecular dynamic simulations to be especially vulnerable to changes in the relative orientation of H1 and its S1 flank. [electronic resource] - European biophysics journal : EBJ Jun 2009 - 601-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1432-1017

10.1007/s00249-009-0414-4 doi


Hydrophobic and Hydrophilic Interactions
Models, Molecular
Peptide Fragments--chemistry
Prions--chemistry
Protein Denaturation
Protein Stability
Protein Structure, Secondary