Synthesis, cytotoxicity, and DNA interactions of new cisplatin analogues containing substituted benzimidazole ligands.

Gümüş, Fatma

Synthesis, cytotoxicity, and DNA interactions of new cisplatin analogues containing substituted benzimidazole ligands. [electronic resource] - Journal of medicinal chemistry Mar 2009 - 1345-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm8000983 doi


Antineoplastic Agents--chemical synthesis
Benzimidazoles--chemical synthesis
Cell Cycle--drug effects
Cell Line, Tumor
Cisplatin--analogs & derivatives
DNA--chemistry
Drug Screening Assays, Antitumor
Humans
Hydrophobic and Hydrophilic Interactions
Ligands
Molecular Structure
Nucleic Acid Conformation
Plasmids
Structure-Activity Relationship