HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.

Yang, Hai-Tao

HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism. [electronic resource] - Clinical and experimental pharmacology & physiology Aug 2009 - 822-7 p. digital

Publication Type: Journal Article

1440-1681

10.1111/j.1440-1681.2009.05150.x doi


Amino Acid Sequence
Amino Acid Substitution
Base Sequence
Blotting, Western
Cell Line
Cytosine--metabolism
ERG1 Potassium Channel
Electrocardiography
Endoplasmic Reticulum--genetics
Ether-A-Go-Go Potassium Channels--genetics
Heterozygote
Humans
Leucine--genetics
Long QT Syndrome--congenital
Microscopy, Confocal
Molecular Sequence Data
Mutation, Missense
Patch-Clamp Techniques
Pedigree
Phenylalanine--genetics
Potassium Channels, Voltage-Gated--metabolism
Protein Subunits
Protein Transport--genetics
Thymine--metabolism
Transfection