Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.

Kuball, Jürgen

Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain. [electronic resource] - The Journal of experimental medicine Feb 2009 - 463-75 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1540-9538

10.1084/jem.20082487 doi


Adoptive Transfer
Animals
CD4-Positive T-Lymphocytes--immunology
Cell Line, Tumor
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Glycosylation
Humans
Mice
Models, Molecular
Neoplasms--immunology
Protein Binding--immunology
Receptors, Antigen, T-Cell--genetics
Reverse Transcriptase Polymerase Chain Reaction
Temperature