Proteasome proteolytic profile is linked to Bcr-Abl expression.

Crawford, Lisa J

Proteasome proteolytic profile is linked to Bcr-Abl expression. [electronic resource] - Experimental hematology Mar 2009 - 357-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1873-2399

10.1016/j.exphem.2008.11.004 doi


Apoptosis
Benzamides
Cell Transformation, Neoplastic
Drug Resistance, Neoplasm
Fusion Proteins, bcr-abl--analysis
Gene Expression Regulation, Neoplastic
Humans
Imatinib Mesylate
K562 Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive--pathology
Piperazines--pharmacology
Protease Inhibitors--pharmacology
Proteasome Endopeptidase Complex--metabolism
Pyrimidines--pharmacology
Tumor Cells, Cultured