Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion.

Amaya, Fumimasa

Periganglionic inflammation elicits a distally radiating pain hypersensitivity by promoting COX-2 induction in the dorsal root ganglion. [electronic resource] - Pain Mar 2009 - 59-67 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1872-6623

10.1016/j.pain.2008.11.013 doi


Analysis of Variance
Animals
Autonomic Fibers, Preganglionic--pathology
Behavior, Animal--drug effects
Biophysics
Cyclooxygenase 2--genetics
Cytokines--pharmacology
Disease Models, Animal
Enzyme Inhibitors--pharmacology
Freund's Adjuvant--adverse effects
Ganglia, Spinal--drug effects
Gene Expression--drug effects
Hyperalgesia--etiology
In Vitro Techniques
Inflammation--complications
Lactones--pharmacology
Male
Pain Measurement
Pain Threshold--physiology
RNA, Messenger--metabolism
Rats
Rats, Sprague-Dawley
Reaction Time--drug effects
Sciatica--complications
Sulfones--pharmacology