New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu, Wenhua

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents. [electronic resource] - Bioorganic & medicinal chemistry Feb 2009 - 1222-31 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1464-3391

10.1016/j.bmc.2008.12.025 doi


Animals
Antineoplastic Agents--chemical synthesis
Cell Line, Tumor
Doxorubicin--pharmacology
Fluorine Radioisotopes--chemistry
Humans
Ligands
Mice
Mice, Inbred BALB C
Phenylcarbamates--chemical synthesis
Positron-Emission Tomography
Radiopharmaceuticals--chemical synthesis
Receptors, sigma--metabolism