Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis.

Coss, Alan

Increased topoisomerase IIalpha expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis. [electronic resource] - Cancer letters Apr 2009 - 228-38 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1872-7980

10.1016/j.canlet.2008.11.018 doi


Adult
Aged
Aged, 80 and over
Antigens, Neoplasm--analysis
Apoptosis
Cell Proliferation
Chromosomal Instability
Colorectal Neoplasms--drug therapy
DNA Topoisomerases, Type II--analysis
DNA-Binding Proteins--analysis
Drug Resistance, Neoplasm
Female
Humans
Male
Middle Aged
Poly-ADP-Ribose Binding Proteins
Receptor, ErbB-2--analysis