The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.

Cunha-Ferreira, Inês

The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4. [electronic resource] - Current biology : CB Jan 2009 - 43-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1879-0445

10.1016/j.cub.2008.11.037 doi


Animals
Blotting, Western
Calcium-Binding Proteins--metabolism
Cell Cycle Proteins--metabolism
Centrioles--physiology
Centrosome--metabolism
DNA Primers--genetics
Drosophila--metabolism
Drosophila Proteins--metabolism
Flow Cytometry
Immunoprecipitation
Mass Spectrometry
Microscopy, Electron, Transmission
Mutagenesis, Site-Directed
Nuclear Proteins--metabolism
Protein Serine-Threonine Kinases--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Staphylococcal Protein A--metabolism
Ubiquitin-Protein Ligases--metabolism